User:Mr. Ibrahem/Autoimmune disease
| Autoimmune disease | |
|---|---|
| Other names | Autoimmune condition |
 | |
| Young woman with the typical "butterfly rash" found in systemic lupus erythematosus | |
| Specialty | Rheumatology, immunology, gastroenterology, neurology, dermatology |
| Symptoms | Depends on the condition. Commonly low grade fever, feeling tired[1] |
| Usual onset | Adulthood[1] |
| Types | List of autoimmune diseases (alopecia areata, celiac disease, diabetes mellitus type 1, Graves' disease, inflammatory bowel disease, multiple sclerosis, psoriasis, rheumatoid arthritis, systemic lupus erythematosus, others)[1] |
| Medication | Nonsteroidal anti-inflammatory drugs, immunosuppressants, intravenous immunoglobulin[1][2] |
| Frequency | 24 million / 7% (USA)[1][3] |
An autoimmune disease is a condition arising from an abnormal immune response to a functioning body part.[1] There are at least 80 types of autoimmune diseases.[1] Nearly any body part can be involved.[3] Common symptoms include low grade fever and feeling tired.[1] Often symptoms come and go.[1]
The cause is generally unknown.[3] Some autoimmune diseases such as lupus run in families, and certain cases may be triggered by infections or other environmental factors.[1] Some common diseases that are generally considered autoimmune include celiac disease, diabetes mellitus type 1, Graves' disease, inflammatory bowel disease, multiple sclerosis, psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.[1][4] The diagnosis can be difficult to determine.[1]
Treatment depends on the type and severity of the condition.[1] Nonsteroidal anti-inflammatory drugs (NSAIDs) and immunosuppressants are often used.[1] Intravenous immunoglobulin may also occasionally be used.[2] While treatment usually improves symptoms, they do not typically cure the disease.[1]
About 24 million (7%) people in the United States are affected by an autoimmune disease.[1][3] Women are more commonly affected than men.[1] Often they start during adulthood.[1] The first autoimmune diseases were described in the early 1900s.[5]
References[edit]
- ^ a b c d e f g h i j k l m n o p q r "Autoimmune diseases fact sheet". Office on Women's Health. U.S. Department of Health and Human Services. 16 July 2012. Archived from the original on 5 October 2016. Retrieved 5 October 2016.
- ^ a b Katz U, Shoenfeld Y, Zandman-Goddard G (2011). "Update on intravenous immunoglobulins (IVIg) mechanisms of action and off- label use in autoimmune diseases". Current Pharmaceutical Design. 17 (29): 3166–75. doi:10.2174/138161211798157540. PMID 21864262.
- ^ a b c d Borgelt, Laura Marie (2010). Women's Health Across the Lifespan: A Pharmacotherapeutic Approach. ASHP. p. 579. ISBN 978-1-58528-194-7. Archived from the original on 2017-09-08.
- ^ Hohlfeld R, Dornmair K, Meinl E, Wekerle H (February 2016). "The search for the target antigens of multiple sclerosis, part 1: autoreactive CD4+ T lymphocytes as pathogenic effectors and therapeutic targets". The Lancet. Neurology. 15 (2): 198–209. doi:10.1016/S1474-4422(15)00334-8. PMID 26724103. S2CID 20082472.
- ^ Ananthanarayan R, Paniker CK (2005). Ananthanarayan and Paniker's Textbook of Microbiology. Orient Blackswan. p. 169. ISBN 9788125028086. Archived from the original on 2017-09-08.