User:Kupirijo/Protein kinase classification
Classification[edit]
Classification of protein kinases can be done either by chemical (enzymatic) activity or structure. Chemical activity classifies protein kinases into the following categories:
| Category | EC number |
|---|---|
| Serine/threonine protein kinase | 2.7.11 |
| Tyrosine protein kinase | 2.7.10 |
| Dual-specificity kinase | 2.7.12 |
| Histidine kinase | 2.7.13 |
With respect to amino-acid sequence and thus structure the following families have been proposed:
| Family | Description |
|---|---|
| CMGC | Cyclin-dependent kinases (CDKs), Mitogen-activated protein kinases (MAP kinases), Glycogen synthase kinases (GSK) and CDK-like kinases |