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One of L. E. Hollister's criterias for establishing that a drug is hallucinogenic is that addictive craving should be absent. --David Hedlund (talk) 03:25, 23 June 2014 (UTC)[reply]
In the interest of uniformity, please correct all N-benzyl compound naming to the established '25X-NBXXX' nomenclature. — Preceding unsigned comment added by 78.156.201.16 (talk) 19:57, 10 January 2014 (UTC)[reply]
Only muscimol and gaboxadol are true GABA-A-Agonists, i.e. bind to the same site of the receptor as GABA itself. The pharmacology of ibotenic acid beside of being a prodrug to muscimol is quite unknown, as far as I know. The "Z-drugs" (es)zopliclone, zolpidem and zaleplon, on the other hand, are not direct agonists, but positive allosteric modulators, just as the benzodiazepines, which allosteric binding site on the GABA-A-receptor they also share. Since this different pharmacological actions lead to huge differences in the subjective effects of those drugs, I really don't think that they should be lumped together. --Diogenes2000 (talk) 17:01, 16 November 2014 (UTC)[reply]
The table lists quite a few entactogens as 5ht2aR agonists, which is not true. They should either get their own section or be left in their seperate templateMDMQualone (talk) 05:24, 5 June 2016 (UTC)[reply]
Semi-protected edit request on 1 December 2020[edit]
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Salvinorin A is not a cannabinoid. It should be removed from the Others/Cannabinoid/Natural section. Lluxull (talk) 05:44, 1 December 2020 (UTC)[reply]