User:Mr. Ibrahem/Tick-borne encephalitis vaccine
 FSME-Immun (European TBE vaccine) | |
| Vaccine description | |
|---|---|
| Target | Tick-borne encephalitis virus |
| Vaccine type | Inactivated |
| Clinical data | |
| Trade names | Encepur N, FSME-Immun CC, others |
  (what is this?) (verify) | |
Tick-borne encephalitis vaccine is a vaccine used to prevent tick-borne encephalitis (TBE).[1] The disease is most common in Central and Eastern Europe, and Northern Asia.[1] More than 87% of people who receive the vaccine develop immunity.[2] It is not useful following the bite of an infected tick.[1] It is given by injection into a muscle.[1]
The World Health Organization (WHO) recommends immunizing all people in areas where the disease is common.[1] Otherwise the vaccine is just recommended for those who are at high risk.[1] Three doses are recommended followed by additional doses every three to five years.[1] The vaccines can be used in people more than one or three years of age depending on the formulation.[1] The vaccine appears to be safe during pregnancy.[1]
Serious side effects are rare.[1] Restlessness is an uncommon side effect in children.[3] Minor side effects may include fever, and redness and pain at the site of injection.[1] Older formulations were more commonly associated with side effects.[1] All tick-borne encephalitis vaccines are inactivated whole virus alum-adjuvanted vaccines.[4]
The first vaccine against TBE was developed in 1937.[1] It is on the World Health Organization's List of Essential Medicines.[5] Per dose it costs £30 in the United Kingdom as of 2021.[3] The vaccine is not available in the United States.[6] Two types are available in Russia and two in Europe.[4]
References[edit]
- ^ a b c d e f g h i j k l m World Health Organization (June 2011). "Vaccines against tick-borne encephalitis : WHO position paper". Weekly Epidemiological Record. 86 (24): 241–56. hdl:10665/241769. PMID 21661276.
{{cite journal}}: Unknown parameter|lay-url=ignored (help) - ^ Demicheli V, Debalini MG, Rivetti A (2009). "Vaccines for preventing tick-borne encephalitis". Cochrane Database Syst Rev (1): CD000977. doi:10.1002/14651858.CD000977.pub2. PMC 6532705. PMID 19160184.
- ^ a b "14. Vaccines". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. p. 1393. ISBN 978-0-85711-413-6.
{{cite book}}: CS1 maint: date format (link) - ^ a b Kollaritsch, Herwig; Heininger, Ulrich (2021). "16. Tick-borne encephalitis vaccines". In Vesikari, Timo; Damme, Pierre Van (eds.). Pediatric Vaccines and Vaccinations: A European Textbook (Second ed.). Switzerland: Springer. pp. 159–170. ISBN 978-3-030-77172-0. Archived from the original on 2022-01-11. Retrieved 2022-01-06.
- ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ "3: Infectious Diseases Related to Travel". CDC Health Information for International Travel 2016. Oxford University Press. June 1, 2015. ISBN 978-0199379156. Archived from the original on June 11, 2016.