User:Mr. Ibrahem/Propylhexedrine

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Mr. Ibrahem/Propylhexedrine
Clinical data
Trade namesBenzedrex, Obesin, others
Other namesHexahydro-desoxyephedrine; Hexahydro-methamphetamine; Hydromethamphetamine; Dimethylcyclo-hexaneethanamine; Cycohexyliso-propylmethylamine; Propylhexedrinum
AHFS/Drugs.comMonograph
Pregnancy
category
  • C
Routes of
administration		Medical: Intranasal, by mouth
Recreational: By mouth, by injection
Legal status
Legal status
  • AU: S4 (Prescription only)
  • CA: Unscheduled
  • US: OTC (nasal inhaler only)
Pharmacokinetic data
Onset of actionWithin 5 min[1]
Elimination half-life4 ± 1.5 hours
Duration of actionUp to 2 hrs[1]
Identifiers
  • (±)-1-cyclohexyl-N-methylpropan-2-amine
Chemical and physical data
FormulaC10H21N
Molar mass155.285 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • N(C(CC1CCCCC1)C)C
  • InChI=1S/C10H21N/c1-9(11-2)8-10-6-4-3-5-7-10/h9-11H,3-8H2,1-2H3 checkY
  • Key:JCRIVQIOJSSCQD-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Propylhexedrine, sold under the brand names Benzedrex among others, is a medication used for a stuffy nose.[1] It is used in the nose.[1] Benefits begin within 5 minutes and may last for up to 2 hours.[1] Use is not recommended for more than three days.[2]

Common side effects include burning and nasal discharge.[1] Other concerns include headache, high blood pressure, and psychosis.[1] Safety in pregnancy is unclear.[1] It works similar to amphetamines by causing small arteries to constrict.[1]

Propylhexedrine came into commercial use in 1949.[3] It is available over the counter.[1] In the United States a delivery device costs about 13 USD as of 2021.[4] It is not a controlled substance in the United States.[1] It has also been used for weight loss and misused by people trying to get high.[5][6][7]

References[edit]

  1. ^ a b c d e f g h i j k l m "Propylhexedrine Monograph for Professionals". Drugs.com. Archived from the original on 27 January 2021. Retrieved 29 October 2021.
  2. ^ "DailyMed - BENZEDREX 09-19-2014- propylhexedrine inhalant". dailymed.nlm.nih.gov. Archived from the original on 26 March 2021. Retrieved 29 October 2021.
  3. ^ MD, Steven B. Karch; Drummer, Olaf (11 November 2015). Karch's Pathology of Drug Abuse. CRC Press. p. 1734. ISBN 978-1-4987-6650-0. Archived from the original on 30 October 2021. Retrieved 29 October 2021.
  4. ^ "Benzedrex Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 29 October 2021.
  5. ^ Dart, Richard C. (2004). Medical Toxicology. Lippincott Williams & Wilkins. p. 1073. ISBN 978-0-7817-2845-4. Archived from the original on 30 October 2021. Retrieved 29 October 2021.
  6. ^ Docherty JR (June 2008). "Pharmacology of stimulants prohibited by the World Anti-Doping Agency (WADA)". British Journal of Pharmacology. 154 (3): 606–22. doi:10.1038/bjp.2008.124. PMC 2439527. PMID 18500382.
  7. ^ Ries, Richard K.; Miller, Shannon C.; Fiellin, David A. (2009). Principles of Addiction Medicine. Lippincott Williams & Wilkins. p. 138. ISBN 978-0-7817-7477-2. Archived from the original on 30 October 2021. Retrieved 29 October 2021.
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