User:Mr. Ibrahem/Pralidoxime
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| Clinical data | |
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| Trade names | ATNAA, DuoDote, Protopam, others |
| Other names | 2-pyridine aldoxime methyl chloride, 1-methylpyridine-6-carbaldehyde oxime |
| AHFS/Drugs.com | Monograph |
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| Drug class | Oxime[1] |
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| Chemical and physical data | |
| Formula | C7H9N2O+ |
| Molar mass | 137.162 g·mol−1 |
| 3D model (JSmol) | |
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Pralidoxime (2-PAM) is a medication used to treat organophosphate, anticholinesterase, and nerve agent poisoning.[1] It is used together with atropine.[1] It is not used for carbamate poisoning.[2] It is given by injection into a vein or muscle.[1]
Common side effects include blurry vision, headache, sleepiness, nausea, fast heart rate, high blood pressure, and pain at the site of injection.[1] It is in the oxime family of medications.[1]
Pralidoxime was approved for medical use in the United States in 1964.[1] In the United States it costs about 90 USD per gram as of 2021.[3] An autoinjector is also available in combination with atropine and diazepam.[4] Some militaries provide these autoinjectors to their soldiers.[4]
References[edit]
- ^ a b c d e f g h i "Pralidoxime Monograph for Professionals". Drugs.com. Archived from the original on 18 January 2021. Retrieved 29 October 2021.
- ^ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1422. ISBN 978-0857114105.
- ^ "Protopam Chloride Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 28 January 2021. Retrieved 29 October 2021.
- ^ a b Gupta, R; Parmar, M (January 2021). "Pralidoxime". PMID 32644334.
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