User:Mr. Ibrahem/Metaxalone
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| Clinical data | |
|---|---|
| Trade names | Skelaxin, others |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a682010 |
| License data |
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| Routes of administration | By mouth |
| Drug class | Muscle relaxant[1] |
| Legal status | |
| Legal status | |
| Pharmacokinetic data | |
| Bioavailability | Unknown |
| Metabolism | Liver |
| Onset of action | Within 1 hr[1] |
| Elimination half-life | 9.2 (± 4.8) hours |
| Duration of action | Up to 6 hrs[1] |
| Excretion | Kidney |
| Identifiers | |
| |
| Chemical and physical data | |
| Formula | C12H15NO3 |
| Molar mass | 221.256 g·mol−1 |
| 3D model (JSmol) | |
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| (verify) | |
Metaxalone, sold under the brand name Skelaxin among others, is a muscle relaxant used to treat pain due to musculoskeletal conditions.[2] It has not been found to be useful in cerebral palsy.[1] It is taken by mouth.[1] It may be used together with rest and physiotherapy.[1]
Common side effects include sleepiness, dizziness, headache, nausea, and irritability.[2] Other side effects may include anaphylaxis, rash, jaundice, serotonin syndrome, and low blood cells.[2] Safety in pregnancy is not clear.[2] Exactly how it works is not known, but it may be due to general depression of the central nervous system.[2]
Metaxalone was approved for medical use in the United States in 1962.[1] In the United States 30 tablets costs about 24 USD.[3] There use; however, is not generally recommended.[4]
References[edit]
- ^ a b c d e f g "Metaxalone Monograph for Professionals". Drugs.com. Archived from the original on 9 August 2020. Retrieved 17 November 2021.
- ^ a b c d e f g h "Skelaxin- metaxalone tablet". DailyMed. 27 April 2018. Archived from the original on 27 October 2020. Retrieved 23 October 2020.
- ^ "Metaxalone Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 25 October 2016. Retrieved 17 November 2021.
- ^ Mitchell, Steve. "Why You Shouldn't Take Soma or Other Muscle Relaxers Every Day". Consumer Reports. Archived from the original on 2020-08-08. Retrieved 2021-11-17.