User:Mr. Ibrahem/Fesoterodine
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| Clinical data | |
|---|---|
| Trade names | Toviaz, others |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a609021 |
| License data |
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| Routes of administration | By mouth |
| Drug class | Antimuscarinic[1] |
| Legal status | |
| Legal status | |
| Pharmacokinetic data | |
| Bioavailability | 52% (active metabolite) |
| Protein binding | 50% (active metabolite) |
| Metabolism | Liver (CYP2D6- and 3A4-mediated) |
| Elimination half-life | 7–8 hours (active metabolite) |
| Excretion | Kidney (70%) and fecal (7%) |
| Identifiers | |
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| Chemical and physical data | |
| Formula | C26H37NO3 |
| Molar mass | 411.586 g·mol−1 |
| 3D model (JSmol) | |
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  (what is this?) (verify) | |
Fesoterodine, sold under the brand name Toviaz among others, is a medication used to treat the symptoms of overactive bladder syndrome (OAB).[1][3] It is a second line medication for this use.[4] It is taken by mouth.[1]
Common side effects include dry mouth and constipation.[1] Other side effects may include urinary retention, trouble sleeping, and dizziness.[1][4] It is not recommended in people with severe liver problems or myasthenia gravis.[3] It is an antimuscarinic and works via the same chemical as tolterodine.[1]
Fesoterodine was approved for medical use in Europe in 2007,[3] the United States in 2008,[1] and Canada in 2012.[5] In the United States it costs about 310 USD per month as of 2021.[6] This amount in the United Kingdom costs the NHS about £26.[4]
References[edit]
- ^ a b c d e f g h i j "Fesoterodine Monograph for Professionals". Drugs.com. Archived from the original on 26 January 2021. Retrieved 23 July 2021.
- ^ "Fesoterodine (Toviaz) Use During Pregnancy". Drugs.com. 7 November 2019. Archived from the original on 29 November 2020. Retrieved 12 August 2020.
- ^ a b c "Toviaz". Archived from the original on 12 November 2020. Retrieved 4 August 2021.
- ^ a b c BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 821. ISBN 978-0-85711-369-6.
{{cite book}}: CS1 maint: date format (link) - ^ "Notice of Decision for TOVIAZ". Archived from the original on 2012-04-23. Retrieved 2012-04-20.
- ^ "Toviaz Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 4 August 2021.