User:Mr. Ibrahem/Dyclonine

Mr. Ibrahem/Dyclonine
Clinical data
Trade names	Dyclone, Sucrets, others
Other names	Dyclonine hydrochloride
AHFS/Drugs.com	Monograph
Routes of; administration	Lozenge
Drug class	Local anesthetic
Legal status
Legal status	US: OTC;
Identifiers
	IUPAC name 1-(4-butoxyphenyl)-3-(1-piperidyl)propan-1-one;
Chemical and physical data
Formula	C18H27NO2
Molar mass	289.419 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(c1ccc(OCCCC)cc1)CCN2CCCCC2;
	InChI InChI=1S/C18H27NO2/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19/h7-10H,2-6,11-15H2,1H3 ; Key:BZEWSEKUUPWQDQ-UHFFFAOYSA-N ;
	(what is this?) (verify)

Dyclonine, also known as dyclocaine, is a local anesthetic used for throat or mouth pain.^[2] It is available as a cough drop.^[2] Effects may begin within 10 minutes and last for up to 30 minutes.^[2]

Common side effects include stinging.^[2] Other side effects may include allergic reactions and jitteriness.^[2] Safety in pregnancy is unclear.^[3] It is neither an ester or an amide.^[3]

Dyclonine was in medical use at least as early as the 1950s.^[4] It is the available over-the-counter under the brand name Sucrets among others.^[2]

References[edit]

^ Society, Swiss Pharmaceutical (2000). Index Nominum 2000: International Drug Directory. Taylor & Francis. p. 378. ISBN 978-3-88763-075-1. Archived from the original on 2022-01-11. Retrieved 2021-12-27.
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ "Dyclonine Monograph for Professionals". Drugs.com. Archived from the original on 25 January 2021. Retrieved 27 December 2021.
^ ^a ^b Logothetis, Demetra D. (15 March 2016). Local Anesthesia for the Dental Hygienist. Elsevier Health Sciences. p. 83. ISBN 978-0-323-43050-0. Archived from the original on 11 January 2022. Retrieved 27 December 2021.
^ GREIFENSTEIN, FE; HARRIS LC, Jr; PARRY, JC (September 1956). "Dyclonine; a new local anesthetic agent: clinical evaluation". Anesthesiology. 17 (5): 648–52. doi:10.1097/00000542-195609000-00002. PMID 13355009.

[1] Society, Swiss Pharmaceutical (2000). Index Nominum 2000: International Drug Directory. Taylor & Francis. p. 378. ISBN 978-3-88763-075-1. Archived from the original on 2022-01-11. Retrieved 2021-12-27.

[AHFS2021-2] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ "Dyclonine Monograph for Professionals". Drugs.com. Archived from the original on 25 January 2021. Retrieved 27 December 2021.

[Logo2016-3] Logothetis, Demetra D. (15 March 2016). Local Anesthesia for the Dental Hygienist. Elsevier Health Sciences. p. 83. ISBN 978-0-323-43050-0. Archived from the original on 11 January 2022. Retrieved 27 December 2021.

[4] GREIFENSTEIN, FE; HARRIS LC, Jr; PARRY, JC (September 1956). "Dyclonine; a new local anesthetic agent: clinical evaluation". Anesthesiology. 17 (5): 648–52. doi:10.1097/00000542-195609000-00002. PMID 13355009.

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