User:Mr. Ibrahem/Desonide

Mr. Ibrahem/Desonide
Clinical data
Trade names	Desonate, DesOwen, Verdeso, others
Other names	Prednacinolone; Hydroxyprednisolone acetonide; Desfluorotriamcinolone acetonide; (11β,16α)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
AHFS/Drugs.com	Monograph
MedlinePlus	a605025
Routes of; administration	Topical
Legal status
Legal status	US: ℞-only;
Identifiers
	IUPAC name (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one;
Chemical and physical data
Formula	C24H32O6
Molar mass	416.514 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C\1\C=C/[C@]2(/C(=C/1)CC[C@H]3[C@H]4[C@](C[C@H](O)[C@H]23)([C@@]5(OC(O[C@@H]5C4)(C)C)C(=O)CO)C)C;
	InChI InChI=1S/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,20+,22-,23-,24+/m0/s1 ; Key:WBGKWQHBNHJJPZ-LECWWXJVSA-N ;
	(what is this?) (verify)

Desonide is a steroid cream used to treat eczema, seborrheic dermatitis, contact dermatitis, and psoriasis.^[1] It comes as a cream, ointment, lotion, and foam.^[1]

Common side effects include burning, folliculitis, acne, and thinning of the skin.^[1] Other side effects may include Cushing’s syndrome and high blood sugar.^[1] Most side effects are mild.^[2] It has low to mid potency and is classified as a group VI corticosteroid in the USA.^[1]^[3]

Desonide was approved for medical use in the United States in 1972.^[1] It is available as a generic medication under various brandnames.^[4]^[1] A 15 gram tube of 0.05% costs about 15 USD as of 2021.^[4]

References[edit]

^ ^a ^b ^c ^d ^e ^f ^g ^h "Desonide Monograph for Professionals". Drugs.com. Archived from the original on 20 September 2020. Retrieved 17 July 2021.
^ Wong VK, Fuchs B, Lebwohl M (2004). "Overview on desonide 0.05%: a clinical safety profile". Journal of Drugs in Dermatology. 3 (4): 393–7. PMID 15303783.
^ Bope, Edward T.; Kellerman, Rick D. (24 November 2015). Conn's Current Therapy 2016. Elsevier Health Sciences. p. PT262. ISBN 978-0-323-35535-3. Archived from the original on 28 August 2021. Retrieved 17 July 2021.
^ ^a ^b "Desonide Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 23 June 2019. Retrieved 17 July 2021.

[AHFS2021-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h "Desonide Monograph for Professionals". Drugs.com. Archived from the original on 20 September 2020. Retrieved 17 July 2021.

[2] Wong VK, Fuchs B, Lebwohl M (2004). "Overview on desonide 0.05%: a clinical safety profile". Journal of Drugs in Dermatology. 3 (4): 393–7. PMID 15303783.

[3] Bope, Edward T.; Kellerman, Rick D. (24 November 2015). Conn's Current Therapy 2016. Elsevier Health Sciences. p. PT262. ISBN 978-0-323-35535-3. Archived from the original on 28 August 2021. Retrieved 17 July 2021.

[GX2021-4] "Desonide Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 23 June 2019. Retrieved 17 July 2021.

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