User:Mr. Ibrahem/Cinchocaine

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Mr. Ibrahem/Cinchocaine
Clinical data
Trade namesCincain, Nupercainal, Nupercaine, Sovcaine, others
Other namesDibucaine, percaine[1]
AHFS/Drugs.comMonograph
Routes of
administration
Topical, intravenous (for animal euthanasia)
Drug classLocal anesthetic (amide)[2]
Legal status
Legal status
Identifiers
  • 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide
Chemical and physical data
FormulaC20H29N3O2
Molar mass343.471 g·mol−1
3D model (JSmol)
  • O=C(c1c2ccccc2nc(OCCCC)c1)NCCN(CC)CC
  • InChI=1S/C20H29N3O2/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24) checkY
  • Key:PUFQVTATUTYEAL-UHFFFAOYSA-N checkY
  (verify)

Cinchocaine, also known as dibucaine, is a local anesthetic used together with a corticosteroid to help with the symptoms of hemorrhoids and pruritus ani.[3] It may also be used for minor burns and insect bites.[4] It is applied to the area affected.[3]

Common side effects include rash and skin irritation.[4] Other side effects may include anaphylaxis.[4] It is an amide.[2] It is one of the stronger but also more toxic local anesthetics.[2]

Cinchocaine was first made in 1929.[1] It is available over the counter and as a generic medication.[4][5] In the United States a 30 gram tube costs about 5 USD as of 2021.[5] In the United Kingdom a version which includes a steroid costs about £6.[3]

References[edit]

  1. ^ a b Woolfson, David; McCafferty, Dermot (1 March 1993). Percutaneous Local Anaesthesia. CRC Press. p. 56. ISBN 978-0-13-656372-3. Archived from the original on 11 January 2022. Retrieved 24 December 2021.
  2. ^ a b c "MeSH Browser". meshb.nlm.nih.gov. Archived from the original on 14 May 2021. Retrieved 24 December 2021.
  3. ^ a b c d BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 101. ISBN 978-0857114105.
  4. ^ a b c d e f "Dibucaine Monograph for Professionals". Drugs.com. Archived from the original on 4 November 2021. Retrieved 24 December 2021.
  5. ^ a b "Compare Dibucaine Prices - GoodRx". GoodRx. Archived from the original on 12 November 2016. Retrieved 24 December 2021.