User:Mr. Ibrahem/Cevimeline

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Mr. Ibrahem/Cevimeline
Clinical data
Pronunciationse vim' e leen[1]
Trade namesEvoxac
AHFS/Drugs.comMonograph
MedlinePlusa608025
Pregnancy
category
  • C
Routes of
administration
By mouth (capsules)
Drug classMuscarinic agonist[1]
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Protein binding<20%
Identifiers
  • (2R,2R)-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]
Chemical and physical data
FormulaC10H17NOS
Molar mass199.31 g·mol−1
3D model (JSmol)
  • O1[C@H](SC[C@@]12CN3CCC2CC3)C
  • InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3/t8-,10-/m1/s1 checkY
  • Key:WUTYZMFRCNBCHQ-PSASIEDQSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Cevimeline, sold under the brand name Evoxac, is a medication used to treat dry mouth due to Sjögren's syndrome or radiation therapy.[1] It is similar to pilocarpine.[2] It is taken by mouth.[1]

Side effects are usually mild and may include increased sweating, runny nose, nausea, diarrhea, headaches, dizziness, visual disturbances, and tiredness.[1] Safety in pregnancy is unclear.[2] It is a muscarinic agonist, which results in increased saliva production.[1]

Cevimeline was approved for medical use in the United States in 2000.[2] It is available as a generic medication.[3] In the United States a month of medication costs about 52 USD as of 2021.[3]

References[edit]

  1. ^ a b c d e f g h "Cevimeline". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. 2012. Archived from the original on 6 May 2021. Retrieved 3 January 2022.
  2. ^ a b c "Cevimeline Monograph for Professionals". Drugs.com. Retrieved 3 January 2022. Cite error: The named reference "AHFS2022" was defined multiple times with different content (see the help page).
  3. ^ a b "Cevimeline Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 26 September 2016. Retrieved 3 January 2022.