User:Mr. Ibrahem/Carboprost
 | |
| Clinical data | |
|---|---|
| Trade names | Hemabate, Tham |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a600042 |
| Pregnancy category |
|
| Routes of administration | Intramuscular |
| Drug class | Oxytocic[1] |
| Legal status | |
| Legal status |
|
| Identifiers | |
| |
| Chemical and physical data | |
| Formula | C21H36O5 |
| Molar mass | 368.514 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
  (what is this?) (verify) | |
Carboprost, sold under the brand name Hemabate among others, is a medication used to treat postpartum bleeding and termination of pregnancy.[1] For postpartum bleeding it is used when oxytocin and ergometrine are not sufficient.[2] For termination it is used in the second trimester when other methods have not worked.[1] It is given by injection into a muscle.[1]
Common side effects include diarrhea, headache, nausea, vasodilation, fever, and abdominal pain.[2][1] Other side effects may include uterine rupture, chest pain, shortness of breath, and ringing in the ears.[2] It is an oxytocic.[1] It works similar to PGF2α by increasing contractions of the uterus.[1]
Carboprost was approved for medical use in the United States in 1979.[1] In the United Kingdom it costs the NHS about £18 per dose as of 2021.[2] This amount in the United States costs about 330 USD.[3]
References[edit]
- ^ a b c d e f g h i j k l "Carboprost Monograph for Professionals". Drugs.com. Archived from the original on 28 January 2021. Retrieved 30 December 2021.
- ^ a b c d e BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 871. ISBN 978-0857114105.
- ^ "Carboprost Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 16 January 2021. Retrieved 30 December 2021.