User:Mr. Ibrahem/Carbachol
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| Clinical data | |
|---|---|
| Trade names | Miostat, others |
| Other names | Carbamylcholine |
| AHFS/Drugs.com | Monograph |
| License data | |
| Pregnancy category |
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| Routes of administration | By mouth (tablets) Solution for injection Eye drop |
| Drug class | Cholinergic agonist[1] |
| Legal status | |
| Legal status |
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| Pharmacokinetic data | |
| Bioavailability | Low |
| Identifiers | |
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| Chemical and physical data | |
| Formula | C6H15ClN2O2 |
| Molar mass | 182.65 g·mol−1 |
| 3D model (JSmol) | |
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| (verify) | |
Carbachol, sold under the brand name Miostat among others, is a medication used to treat glaucoma or during eye surgery.[1] Usually other agents such as pilocarpine or acetylcholine preferred.[1] It is used as an eye drop or injected into the eye.[1]
Common side effects include eye discomfort, headache, blurry vision, trouble seeing in low light, and red eyes.[1] Other side effects may include allergic reactions, retinal detachment, diarrhea, low blood pressure, sweating, and arrhythmias.[1] Safety in pregnancy is unclear.[1] It is a cholinergic agonist that binds and activates acetylcholine receptors.[1]
Carbachol was approved for medical use in the United States in 1972.[1] It is on the World Health Organization's List of Essential Medicines as an alternative to pilocarpine.[2] In the United States the solution for injection into the eye costs about 27 USD per dose as of 2021.[3]
References[edit]
- ^ a b c d e f g h i j k "Carbachol Monograph for Professionals". Drugs.com. Archived from the original on 29 April 2021. Retrieved 29 December 2021.
- ^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.
- ^ "Miostat Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 17 January 2021. Retrieved 29 December 2021.