User:Mr. Ibrahem/Benzocaine
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| Clinical data | |
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| Trade names | Anbesol, Lanacane, Orajel, others |
| AHFS/Drugs.com | Topical: Monograph ENT: Monograph |
| Routes of administration | Topical, by mouth |
| Drug class | Local anesthetic (ester)[1] |
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| Identifiers | |
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| Chemical and physical data | |
| Formula | C9H11NO2 |
| Molar mass | 165.192 g·mol−1 |
| 3D model (JSmol) | |
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Benzocaine, sold under the brand name Orajel amongst others, is a local anesthetic.[2][3] Applied to the skin it may be used to help with minor skin injury, hemorrhoids, and premature ejaculation.[2] It may also be used mouth or ear pain.[3] Use in not recommended in those under 2 years old.[3]
While generally well tolerated, contact dermatitis may occur.[2] Other side effects may include methemoglobinemia, seizures, and respiratory depression.[2] Safety in pregnancy is unclear.[4] Use by the mom when breastfeeding is unlikely to be harmful.[5] It is an ester.[1]
Benzocaine was first made in 1890 in Germany and approved for medical use in 1902.[6] It is available as a generic medication and over the counter.[2][3] It is commonly used used many brand names.[1][3] In the United States a tube of 28 grams of 20% costs about 7 USD as of 2022.[7]
References[edit]
- ^ a b c McFadden, John; Puangpet, Pailin; Pongpairoj, Korbkarn; Thaiwat, Supitchaya; Lee, Shan Xian (January 21, 2020). Common Contact Allergens: A Practical Guide to Detecting Contact Dermatitis. John Wiley & Sons. p. 297. ISBN 978-1-119-40566-5. Archived from the original on January 11, 2022. Retrieved January 9, 2022.
- ^ a b c d e f g "Benzocaine (Topical) Monograph for Professionals". Drugs.com. Archived from the original on March 4, 2021. Retrieved January 9, 2022.
- ^ a b c d e f "Benzocaine (EENT) Monograph for Professionals". Drugs.com. Archived from the original on April 17, 2021. Retrieved January 9, 2022.
- ^ "Benzocaine topical Use During Pregnancy". Drugs.com. Archived from the original on April 22, 2021. Retrieved January 9, 2022.
- ^ "Benzocaine". Drugs and Lactation Database (LactMed). National Library of Medicine (US). 2006. Archived from the original on February 26, 2021. Retrieved January 9, 2022.
- ^ Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 475. ISBN 9783527607495. Archived from the original on December 29, 2016. Retrieved May 26, 2021.
- ^ "Compare Benzocaine Prices - GoodRx". GoodRx. Retrieved January 9, 2022.