Talk:Trinucleotide repeat expansion

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Untitled[edit]

this page is also a section of http://en.wikipedia.org/wiki/Trinucleotide_repeat_disorder.

I edited this page to remove the following section

In 2006,a model of expanding the triplets by involving RNA:DNA intermediate formed in repeat transcription or in post-transcription was proposed. ref name="pmid16450581">Pan XF (2006). "Mechanism of trinucleotide repeats instabilities: the necessities of repeat non-B secondary structure formation and the roles of cellular trans-acting factors". Acta Genetica Sin. 33 (1): 1–11. doi:10.1016/S0379-4172(06)60001-2. PMID 16450581.ref> , and similar ideas turned to be a fashion ongoing issue of the mechanism studies ever since

Not only is the English quite poor, but the cited article is highly obscure, having only 7 citations as of Jan 2014 according to Google Scholar.

I left the citation of McIvor et al. (2010) in RNA Biol. But probably this should also be removed; it has only 15 citations in an admittedly short period: three years. 134.174.140.133 (talk) 18:25, 14 February 2014 (UTC)[reply]

trinucleotide repeat sequence examples.[edit]

Huntington CAG repeat. Fragile X CGG repeat Mytonica dystrophica CTG repeat Spinocerebellar ataxia CAG repeat Fadric ataxia GAA repeat Dr.lalitmohan7 (talk) 14:29, 15 March 2015 (UTC)[reply]