Talk:Timeline of human vaccines/Archive 1

Archive 1

Rotavirus

Time for discussion on last vaccine entry. This list is for vaccines that were viable, not failed experiments. There are many vaccines that are developed that may innoculate against a disease but cause unintended side effects; because of this, they are pulled from the marketplace or never released. According to the rotavirus article, the only safe & effective vaccines were finally developed in 2006 - Rotarix & RotaTeq. The 1998 vaccine Rotashield was not effective and had serious severe side effects. A vaccine is not considered viable until it meets certain criteria, hence why the 2006 discovery of vaccines that actually work became relevant. Rotashield was pulled from marketplace availibility - one of the introducitons criteria for listing vaccines in the article. Vaccines are discovered that do innoculate against the pathogen, but they have to be safe enough to actually go into use. Sometimes these drugs are only found to be unsafe after being released across the world, and so we haven't had a vaccine for rotavirus until this year. This is not a list for failed attempts but effective vaccines. Informationplusgood 03:09, 3 April 2006 (UTC)

That just not true. Rotashield was entirely successful, widely used - in fact was a vaccine schedule required vaccination in the US. And it was safer than most early vaccines - and even some still in use. However, it was removed from the market and safer alternatives were introduced - so have a number of other first vaccines on this list. It is still the first vaccine for the disease. Please read the entire article about the controversy over the withdrawal where the high standards of the US were blamed for the deaths of third world children. Rmhermen 03:15, 3 April 2006 (UTC)

Untitled

Any reason why anthrax is listed twice? once in 1881 and again in 1954. Regards, 69.29.196.143 (talk) 23:10, 8 April 2008 (UTC)

Need dates for vaccines against typhoid, cholera, Japanese encephalitis. Rmhermen 19:05, Nov 12, 2003 (UTC)

Found them. What others are there? Rmhermen 19:40, Nov 12, 2003 (UTC)

Vaccines are currently in human testing for SARS, Ebola, HIV, West Nile, HPV (cervical cancer), bird flu, malaria, strep A. We should add dates when they come on the market (if they succeed). Rmhermen 00:50, 2 Jun 2004 (UTC)

According to this, 1917 was the date of the first epidemic typhus vaccine, created by Rudolf Weigl, a Polish scientist. Is it just bullshit or should the date be changed here? Jkeiser 07:33, 9 Jun 2004 (UTC)

I couldn't find any mention of Weigl and 1917 in that source. However it does say that wide-scale human testing began in 1933 and that it was first used in populations at the beginning of WWII. So our date of 1937 for the proven vaccine seems right on. Rmhermen 12:34, Jun 9, 2004 (UTC)

Odd, I'm not sure where I got that number from now. Anyway, the dates I did pick out from the various articles after re-reading everything--including the one I mentioned before indicates that the earliest date that it was first used in a major way was in China in 1936. But I am inferring that from the publishing date of 1936; nothing explicitly says "we first used this vaccine in 1936." So it could be 1937 or so. I'll leave it alone until I find something more concrete. Thanks. Jkeiser 07:16, 10 Jun 2004 (UTC)

Varicella

I think the chickenpox date is wrong. Please check the article. —Preceding unsigned comment added by 12.47.208.50 (talk) 17:29, 25 July 2008 (UTC) No, that date is corect. " varicella vaccine, derived from the Oka strain, was first described by Takahashi in 1974." The date in the chickenpox article is wrong - 1995 is the date it was approved for use in the U.S. Rmhermen (talk) 20:48, 25 July 2008 (UTC)

Vaccines under development to watch for

• SARS
• Ebola - phase I
• HIV - maybe by 2020[1]
• West Nile - early Phase I - II in 2013
• malaria - Phase III trial in 2009
• strep A - Phase I/II trials in 2013
• dengue fever - Phase III trial in 2012
• C. Difficile - phase II
• E. Coli - phase II
• Herpes simplex - phase I
• Hep C - phase II
• botulism - phase II
• cytomegalovirus - phase I
• staphalococcus aureus - phase I
• Helicobacter pylori - phase I
• marburg - phase
• norovirus - phase I/II
• parvovirus - phase I/II
• shigella - phase I
• cytomegalovirus - phase II
• tularemia - phase I
• leishmaniasis - phase I

Rmhermen (talk) 16:48, 5 November 2013 (UTC)

Thanks Rmhermen, this is a helpful list to have included on the talk page. LT910001 (talk) 22:13, 5 November 2013 (UTC)

West Nile virus - phase I (2015) [2] Rmhermen (talk) 21:26, 2 February 2016 (UTC)