Talk:Smoothened

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Untitled[edit]

Is it actually a G-protein coupled receptor? It's just that 7TM redirects to GPCR. Aaadddaaammm 08:56, 20 October 2006 (UTC)[reply]

Yes, smo is pretty well defined as a GPCR. See PMID: 17094938. Also all GPCRs are 7TM proteins. I'm not sure if the reverse is true, but there are none I know of. 67.194.58.140 (talk) 19:08, 30 April 2008 (UTC)[reply]

Found in which species?[edit]

The article doesn't seem to mention anywhere which species have the gene/protein. Is it all animals? All vertebrates and some invertebrates but not some other things? And is this the name of the protein, the gene, or both?

The short description, which I'm about to change if I can word it less misleadingly, currently reads Protein-coding gene in the species Homo sapiens, which seems an odd way to describe something also found in fruit flies.

For now I'll change it to something like Gene found in humans and other animals so it's at least not restricted to humans any more.

By the way, I've seen a few articles with the exact same short description to this one, often for genes that don't seem from their article to be restricted to humans at all. Unfortunately I'm not a biologist, but I think it might be sensible if someone who is had a look through them. Musiconeologist (talk) 16:18, 17 March 2024 (UTC)[reply]