Talk:Postsynaptic potential

Physiology Low‑importance

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Neuroscience Mid‑importance

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Deletion of this page[edit]

I don't know what compelled MZMcBride to originally erase this discussion page, but if it happens again, I will report it.

Spatial summation section misleading[edit]

There is some serious wording issues with regard to the below section

Spatial summation: If a cell is receiving input at two synapses that are near each other, their postsynaptic potentials add together. If the cell is receiving two excitatory postsynaptic potentials, they combine so that the membrane potential is depolarized by the sum of the two changes. If there are two inhibitory potentials, they also sum, and the membrane is hyperpolarized by that amount. If the cell is receiving both inhibitory and excitatory postsynaptic potentials, they can cancel out, or one can be stronger than the other, and the membrane potential will change by the difference between them.

I find it leads the reader to assume that at some point it will discuss what happens when inputs arrive at two distant synapses. Furthermore, this seems to be based more on reasoning than proof. Do inputs of opposite signs simply cancel eachother out? It's a little long winded, it could all be summed up with a simple 'their magnitudes are summed together'.

Reversal Potential[edit]

In From Neuron to Brain (Nicholls et. al. 2001) and Neuroscience (Purves et. al. 2007), they make reference to the reversal potential for end plate currents (EPC) (postsynaptic currents in muscle cells) but then there's a vague reference to how everything is more or less the same with postsynaptic currents. Now, my question is this: The current that flows through the receptors synaptic receptors of a neuron (PSC), is it also determined by the below equation (which is intended for EPCs)

EPC=g * (V_m-E_rev)

where g is the total channel conductance (how much current the receptors conduct) of all the receptors, V_m is the membrane potential, and E_rev is the reversal potential (membrane potential at which the channel no longer conducts any net charge)

Thanks. Paskari (talk) 14:21, 2 September 2008 (UTC)[reply]

page unreferenced for years[edit]

The whole page is unreferenced for years. How can anybody even discuss it ?--Wuerzele (talk) 04:23, 26 February 2015 (UTC)[reply]