Talk:Lupeol

Rauvolfia tetraphylla[edit]

User:223.180.156.252 has added the following message to WP:New contributors' help page/questions:"Brahmachari et al.,2011 reported the occurrence of a pentacyclic triterpenoid, lupeol from the ripe fruits of Rauvolfia tetraphylla for the first time. ref: Lupeol, a pharmaceutically potent triterpenoid, from the ripe fruits of Rauvolfia tetraphylla L. (Apocynaceae) Goutam Brahmachari*,Lalan C. Mandal, Rajiv Roy, Shyamal K. Jash, Avijit Mondal, Sasadhar Majhi and Dilip Gorai, Journal of Indian Chemical Society, 2011, 88, 303-305" This appears to be reliably supported, but I do not know enough about the subject to know whether it is notable (i.e. is it the third fruit that have been found to contain lupeol, or one of hundreds). --ColinFine (talk) 22:21, 16 October 2011 (UTC)[reply]

Potential references[edit]

Gallo, M.B.C. / Sarachine, M.J. “Biological Activities of Lupeol”, International Journal of Biomedical and Pharmaceutical Sciences (2009),3 (Special Issue 1):46-66.
Saleem, M. “Lupeol, a novel anti-inflammatory and anti-cancer dietary triterpene”, Cancer letters (2009),285(2):109-115.

--Ronz (talk) 19:27, 23 May 2012 (UTC)[reply]

External links modified[edit]

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Coupling catalyst needs another lithium: Li2 Cu Cl4; Missing -CH2-[edit]

Step one in the synthesis scheme shown (Grignard coupling to vinyl acetate) has two errors. There is a missing methylene: it should be an allylic acetate, not a vinyl acetate. The reaction actually uses Li2CuCl4 dilithium tetrachlorocuprate as catalyst. The catalyst over the arrow shows Li Cu Cl4 and should be corrected to Li2CuCl4 (made from 2 LiCl + CuCl2 --> Li2CuCl4 in THF). (Thank you to whoever submitted the reaction scheme. It's a lot of work to draw it out. Sometimes an error slips through.) AdderUser (talk) 19:15, 10 November 2020 (UTC)[reply]