Talk:Keratinocyte

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Medicine: Dermatology Mid‑importance

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Molecular Biology: MCB

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Please show a source that basal layer are stem cells.[edit]

Thanks. —Preceding unsigned comment added by 75.50.56.1 (talk) 20:38, 4 December 2007 (UTC)[reply]

Flattening[edit]

Is the progressive flattening of keratinocytes as they make their way to the surface a consequence of the combination of pressure from below due to new cells being made at the basal layer, and external atmospheric pressure?

If it is, could someone add something to this effect? Many thanks.

Notreallydavid (talk) 19:20, 5 August 2015 (UTC)[reply]

--
I was just reading in my anatomy book^[1]. It just says that extensive changes take place in the flattened cell layers such as:

Nuclei become pyknotic (and begin to disintegrate).
Organelles disintegrate such as Ribosomes, membrane bound mitochondria, and Golgi bodies.
Cytokeratin Filament bundles become more compact and associated with irregular, densely staining keratohyalin granules.
Round granules appear in the cytoplasm.

Maybe an anatomy phD. can pick up and explain the flattening more, but I have a feeling it'll just be from the pressure plus loss of organelles inside the cell.---- Paul K. | MechE | MSY-2 | Chemist | Let's talk 13:23, 24 September 2019 (UTC)[reply]

References

^ Gray's anatomy : the anatomical basis of clinical practice (Forty-firstition ed.). p. 144. ISBN 9780702052309.

[1] Gray's anatomy : the anatomical basis of clinical practice (Forty-firstition ed.). p. 144. ISBN 9780702052309.

[1]