Talk:Hemagglutinin (influenza)

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Untitled[edit]

This page could use a link to a section on the process of Hemagglutination.. I could use a section on Hemagglutination! This process is alluded to in the title "Functions and mechanism of action", but more information regarding the process regarding its effects/implications on the immune system, the host, the tissues, physical chemistry of interaction.. A subsection of Hemagglutination might also include a link to 'synctia' or perhaps just inclusion of synctia under Hemagglutination.

"unidentified glycoprotein"[edit]

Also on the subject of hemagglutinin, it is my understanding that hemagglutinin binds to sialic acid (neuraminic acid) on the surface of respiratory epithelial cells. Am I misreading it or does this article imply that sialic acid on the surface of the virus binds to an unknown surface glycoprotein? Thanks.

Sialic acid is a component of an unknown surface glycoprotein, yes. As for an article on hemagglutination, try suggesting it here: Wikipedia:WikiProject_Molecular_and_Cellular_Biology/Requested_articles Bendž |Ť 18:22, 14 May 2007 (UTC)[reply]

epitope tag?[edit]

Should this page mention hemagglutinin's widespread use as an epitope tag or would that be more appropriate in another article? 128.231.88.4 21:33, 4 November 2006 (UTC)[reply]

Differences between varieties?[edit]

There are 16 HA antigens known, but what distinguishes between them? How similar are they to each other, and how much variation is there within each antigen class? -- 20:37, 27 August 2007 (UTC)

There are 18 know HA subtypes as of now, they are distinguished through classical hemagglutination inhibition assays from immunized ferrets (where sera from ferrets immunized against H1 would not inhibit H2 or any other subtype). Two of the subtypes are hypothetical proteins only seen as sequences isolated from bats (H17 and H18). These HAs are grouped further into two groups based on broader antigenic differences, classified as group 1 and group 2. -- 15:52, 9 May 2024 UTC [refresh]

good job guys[edit]

I'm a first year science student at McMaster University, and my biology professor has put a large emphasis on virology for our first midterm. I just thought I'd mention that he put in his course notes that Wikipedia is "great" for information on influenza, mentioning this article in particular. I thought it was pretty amazing that he would consider any Wikipedia article to be a reliable source for exam review, so congratulations on the good work. —Preceding unsigned comment added by 130.113.193.28 (talk) 18:14, 14 October 2007 (UTC)[reply]

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