Talk:HES1

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Untitled[edit]

Statement "The E47-Hes and Mash1-Hes heterodimer complexes cannot bind DNA, and therefore repress transcription.[3]" looks odd after it was said that Hes represses transcription due to C-terminal WRPW domain when Hes binds DNA. Please, elucidate, does Hes inhibits transcription because of binding or not-binding. — Preceding unsigned comment added by Prijutme4ty (talk • contribs) 13:32, 2 November 2015 (UTC)[reply]