Talk:Deamination

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Untitled[edit]

Could deamination be another name for Nitrosation? If this turn out to be the case, purge Nitrosation. gathima 16:05, 16 Jun 2005 (UTC)

oxidative deamination[edit]

This page apears to describe Deamination as the process of turning Amino Acids in to nothing more the Ammonia.

Other documents such as http://www.elmhurst.edu/~chm/vchembook/632oxdeam.html

..describe deamination in more detail.

Here are some addition points that this document should cover:

- The conversion of amino acids to "the corresponding keto acid" and the processes there in. - The variouse types of deamination, if there is more then one, such as "Oxidative deamination". - The difference between Deamination within the Liver and all other tissues. - Oxidative Deamination's occurance on glutamic acid and anything else if occurs on - links and refernces to pages such as "glutamic acid" and "transamination reactions" - glutamate dehydrogenase - allosterically controlle - Definitions of, or links to pages with definitions of, ATP and ADP.

Hope im not missing something here =]

This page is a mess[edit]

I know, I should do something about it then. I'm not exactly sure what. It combines deamination of bases in DNA with more or less completely unrelated material about deamination of metabolites in the liver. It needs some kind of generic intro about the process of deamination. Then the specific sorts mentioned here could go in sections. It would be nice if someone with a bit more recent organic chem knowledge than mine would write the intro.Agathman (talk) 16:31, 9 May 2009 (UTC)[reply]

Amine? You mean, amino.[edit]

The first sentence defines deamination as "the removal of an amine group from a molecule", whereas Merriam-Webster and others define it as "to remove an amino group from (a compound)". Not the same thing, people! Morenus (talk) 20:54, 21 October 2013 (UTC)[reply]

Mistake ?[edit]

I think there's a mistake in the consequence of deamination of a Guanine into Xanthine. I read in different references that Xanthine pairs with Cytosine and that therefore deamination of guanine has no mutational consequences. Sources : Biochemistry 5th ed - Jeremy M. Berg, John L. Tymoczko, Lubert Stryer

Other mutagens act by chemically modifying the bases of DNA. For example, nitrous acid (HNO2) reacts with bases that contain amino groups. Adenine is oxidatively deaminated to hypoxanthine, cytosine to uracil, and guanine to xanthine. Hypoxanthine pairs with cytosine rather than with thymine (Figure 27.43). Uracil pairs with adenine rather than with guanine. Xanthine, like guanine, pairs with cytosine. Consequently, nitrous acid causes A-T G-C transitions.

Also here https://learning.uonbi.ac.ke/courses/SZL311/scormPackages/path_2/14192_deaminating_agents_eg_hno2.html

and

http://www.eplantscience.com/index/genetics/mutations_molecular_level_mechanism/effect_of_chemical_mutagens_on_nucleotide_sequence.php — Preceding unsigned comment added by 2A01:E35:2E38:50E0:9477:2F90:255D:30CD (talk) 20:44, 4 November 2014 (UTC)[reply]

Additional enzymes?[edit]

The article mainly deals with non-enzymatic deamination and its consequences (repair). Thereby "Additional enzymes..." sounds wrong in this context. Maybe remove the "additional"? — Preceding unsigned comment added by Abisko00 (talk • contribs) 16:11, 18 June 2018 (UTC)[reply]