Talk:Bradykinin receptor

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What cell is the receptor at?[edit]

What cell do you find B1 and B2? And what causes the receptor to be created de novo? (It can't be just bradykinin binding to its receptor since there is no receptor yet, right?) — Preceding unsigned comment added by 24.248.198.18 (talk) 20:06, 8 June 2011 (UTC)[reply]

According to PMID 19561616, B1 is primarily expressed in immune cells where as B2 is more widely distributed. According to PMID 15705059, NF-κB (a transcription factor involved in stress response), may up-regulate the expression of B1, so that if NF-κB is not activated, no B1 is expressed, but if NF-κB if activated, expression of B1 is increased. Boghog (talk) 20:24, 8 June 2011 (UTC)[reply]