TMPRSS11B

TMPRSS11B
Identifiers
Aliases	TMPRSS11B, transmembrane protease, serine 11B, transmembrane serine protease 11B, HATL5
External IDs	HomoloGene: 131255; GeneCards: TMPRSS11B; OMA:TMPRSS11B - orthologs
Gene location (Human) Chr. Chromosome 4 (human) Band 4q13.2 Start 68,226,653 bp End 68,245,694 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oral cavity body of tongue gums superior surface of tongue amniotic fluid vagina sperm thymus palpebral conjunctiva minor salivary glands n/a More reference expression data BioGPS n/a
Gene ontology Molecular function peptidase activity hydrolase activity serine-type peptidase activity serine-type endopeptidase activity Cellular component integral component of plasma membrane membrane extracellular region extracellular exosome integral component of membrane plasma membrane Biological process proteolysis biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 132724 n/a Ensembl ENSG00000185873 n/a UniProt Q86T26 n/a RefSeq (mRNA) NM_182502 n/a RefSeq (protein) NP_872308 n/a Location (UCSC) Chr 4: 68.23 – 68.25 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Transmembrane protease, serine 11B is a protein that in humans is encoded by the TMPRSS11B gene.

Further reading

• Shiffman D, O'Meara ES, Bare LA, Rowland CM, Louie JZ, Arellano AR, Lumley T, Rice K, Iakoubova O, Luke MM, Young BA, Malloy MJ, Kane JP, Ellis SG, Tracy RP, Devlin JJ, Psaty BM (2008). "Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study". Arterioscler. Thromb. Vasc. Biol. 28 (1): 173–9. doi:10.1161/ATVBAHA.107.153981. PMC 2636623. PMID 17975119.
• Luke MM, O'Meara ES, Rowland CM, Shiffman D, Bare LA, Arellano AR, Longstreth WT, Lumley T, Rice K, Tracy RP, Devlin JJ, Psaty BM (2009). "Gene variants associated with ischemic stroke: the cardiovascular health study". Stroke. 40 (2): 363–8. doi:10.1161/STROKEAHA.108.521328. PMC 2881155. PMID 19023099.