KIF4B

KIF4B
Identifiers
Aliases	KIF4B, kinesin family member 4B
External IDs	OMIM: 609184 HomoloGene: 129673 GeneCards: KIF4B
Gene location (Human)
Chr.	Chromosome 5 (human)
End	155,018,141 bp
RNA expression pattern
	Top expressed in
	testicle;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	microtubule binding; DNA binding; nucleotide binding; ATP binding; plus-end-directed microtubule motor activity; microtubule motor activity; ATPase activity;
Cellular component	nuclear matrix; cytoplasm; cytosol; microtubule; cytoskeleton; kinesin complex; nucleus; nucleoplasm; intercellular bridge;
Biological process	mitotic cytokinesis; microtubule-based movement; antigen processing and presentation of exogenous peptide antigen via MHC class II; mitotic spindle midzone assembly; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; mitotic spindle organization;
	Sources:Amigo / QuickGO
Orthologs
	285643
	n/a
	ENSG00000226650
	n/a
	Q2VIQ3
	n/a
	NM_001099293
	n/a
	NP_001092763
	n/a
	Wikidata
View/Edit Human

KIF4B is a human protein encoded by the gene KIF4B. It is part of the kinesin family of motor proteins.

Function[edit]

KIF4B and the closely related protein KIF4A are essential for regulating anaphase spindle dynamics during mitosis.^[3]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000226650 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhu, Changjun; Zhao, Jian; Bibikova, Marina; Leverson, Joel D.; Bossy-Wetzel, Ella; Fan, Jian-Bing; Abraham, Robert T.; Jiang, Wei (July 2005). "Functional Analysis of Human Microtubule-based Motor Proteins, the Kinesins and Dyneins, in Mitosis/Cytokinesis Using RNA Interference". Molecular Biology of the Cell. 16 (7): 3187–3199. doi:10.1091/mbc.e05-02-0167. ISSN 1059-1524. PMC 1165403. PMID 15843429.

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