Dermatopathic lymphadenopathy

Dermatopathic lymphadenopathy
Dermatopathic lymphadenopathy
Other names	Dermatopathic lymphadenitis
	Micrograph showing dermatopathic lymphadenopathy with the characteristic paracortical histiocytosis and melanin-laden macrophages. H&E stain.
Specialty	Dermatology

In pathology, dermatopathic lymphadenopathy, is lymph node pathology due to skin disease.

Cause[edit]

Also known as lipomelanotic reticulosis or Pautrier-Woringer disease, represents a rare form of benign lymphatic hyperplasia associated with most exfoliative or eczematoid inflammatory erythrodermas, including pemphigus, psoriasis, eczema, neurodermatitis, and atrophia senilis.

Diagnosis[edit]

Dermatopathic lymphadenopathy is diagnosed by a lymph node biopsy. It has a characteristic pattern of histomorphology and immunohistochemical staining:

Paracortical histiocytosis
Melanin-laden macrophages
Eosinophils
Plasma cells (medulla of lymph node)

Differential diagnosis[edit]

Treatment[edit]

The treatment is based on the underlying cause.

References[edit]

^ ^a ^b Lee, SW.; Park, MC.; Kim, H.; Park, YB.; Lee, SK. (2007). "Dermatopathic lymphadenopathy in a patient with adult onset Still's disease". Clin Exp Rheumatol. 25 (2): 312–14. PMID 17543161.

External links[edit]

Dermatopathic lymphadenitis - pathconsultddx.com.

[pmid17543161-1] Lee, SW.; Park, MC.; Kim, H.; Park, YB.; Lee, SK. (2007). "Dermatopathic lymphadenopathy in a patient with adult onset Still's disease". Clin Exp Rheumatol. 25 (2): 312–14. PMID 17543161.

[1]